Overview

  • Product name
  • Description
    Rabbit polyclonal to Granuphilin
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide derived from internal sequence of Human SYTL4.

  • Positive control
    • Extracts from NIH-3T3 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab110519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 76 kDa.

Target

  • Function
    Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
  • Sequence similarities
    Contains 2 C2 domains.
    Contains 1 FYVE-type zinc finger.
    Contains 1 RabBD (Rab-binding) domain.
  • Cellular localization
    Membrane. Cell membrane. Cytoplasmic vesicle > secretory vesicle membrane. Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp451P0116 antibody
    • Exophilin-2 antibody
    • FLJ40960 antibody
    • Granuphilin antibody
    • SLP4 antibody
    • Synaptotagmin like 4 antibody
    • Synaptotagmin-like protein 4 antibody
    • Sytl4 antibody
    • SYTL4_HUMAN antibody
    see all

Images

  • All lanes : Anti-Granuphilin antibody (ab110519)

    Lane 1 : Extracts from NIH-3T3 cells
    Lane 2 : Extracts from NIH-3T3 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 76 kDa

References

This product has been referenced in:
  • Jafarian A  et al. The Generation of Insulin Producing Cells from Human Mesenchymal Stem Cells by MiR-375 and Anti-MiR-9. PLoS One 10:e0128650 (2015). WB . Read more (PubMed: 26047014) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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