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Rabbit polyclonal to Granuphilin
Predicted to work with:
Synthetic peptide derived from internal sequence of Human SYTL4.
Extracts from NIH-3T3 cells
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 76 kDa.
Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
Contains 2 C2 domains.
Contains 1 FYVE-type zinc finger. Contains 1 RabBD (Rab-binding) domain.
Membrane. Cell membrane. Cytoplasmic vesicle > secretory vesicle membrane. Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles.
Information by UniProt
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