Anti-Granzyme A antibody (ab73420)

Overview

  • Product nameAnti-Granzyme A antibody
    See all Granzyme A primary antibodies
  • Description
    Rabbit polyclonal to Granzyme A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Non Human Primates
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 200 to the C-terminus of Human Granzyme A.

    (Peptide available as ab90219.)

  • Positive control
    • This antibody gave a positive signal in Jurkat Whole Cell Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab73420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).

Target

  • FunctionThis enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Involved in apoptosis.
  • Sequence similaritiesBelongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localizationSecreted. Cytoplasmic granule.
  • Information by UniProt
  • Database links
  • Alternative names
    • CTL tryptase antibody
    • CTLA3 antibody
    • Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody
    • Cytotoxic T lymphocyte associated serine esterase 3 antibody
    • Cytotoxic T lymphocyte proteinase 1 antibody
    • Cytotoxic T-lymphocyte proteinase 1 antibody
    • Fragmentin 1 antibody
    • Fragmentin-1 antibody
    • GRAA_HUMAN antibody
    • Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody
    • Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3; Hanukah factor serine protease) antibody
    • Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3) antibody
    • Granzyme A antibody
    • Granzyme A precursor antibody
    • Granzyme-1 antibody
    • GZMA antibody
    • H factor antibody
    • Hanukah factor serine protease antibody
    • Hanukkah factor antibody
    • HF antibody
    • HFSP antibody
    • TSP1 antibody
    see all

Anti-Granzyme A antibody images

  • Anti-Granzyme A antibody (ab73420) at 1 µg/ml + Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 29 kDa
    Observed band size : 29 kDa
    Additional bands at : 28 kDa (possible cleavage fragment),70 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Granzyme A antibody (ab73420)

ab73420 has not yet been referenced specifically in any publications.

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We do not have this type of clinical data as our products are for in vitro use. A literature search should be able to provide you with this kind of information.


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