Granzyme B overexpression 293T lysate (whole cell) (ab94041)

Overview

  • Product nameGranzyme B overexpression 293T lysate (whole cell)
    See all Granzyme B lysates
  • Description
    Granzyme B overexpression lysate
  • General notesab94041 is a 293T cell transfected lysate in which Human Granzyme B has been transiently over-expressed using a pCMV-Granzyme B plasmid. The lysate is provided in 1X Sample Buffer. Note: For more detailed how the transfected lysate was prepared view preparation notes
  • Tested applicationsSuitable for: WBmore details

Properties

  • BackgroundFunction: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. Similarity: Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain.

Associated products

Applications

Our Abpromise guarantee covers the use of ab94041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.

Granzyme B overexpression 293T lysate (whole cell) images

  • ab94041 at 15µg/lane on an SDS-PAGE gel.

References for Granzyme B overexpression 293T lysate (whole cell) (ab94041)

ab94041 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"