Overview

  • Product nameAnti-Granzyme H antibody
    See all Granzyme H primary antibodies
  • Description
    Mouse polyclonal to Granzyme H
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human Granzyme H.
    Database link: NP_219491.1

  • Positive control
    • Human spleen tissue lysate, Granzyme H transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab89607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.

Target

  • FunctionCytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
  • Tissue specificityConstituvely expressed in NK cells.
  • Sequence similaritiesBelongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localizationCytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cathepsin G like 2 antibody
    • Cathepsin G-like 2 antibody
    • CCP X antibody
    • CCP-X antibody
    • CGL 2 antibody
    • CGL2 antibody
    • CSP C antibody
    • CSP-C antibody
    • CTLA1 antibody
    • CTSGL2 antibody
    • Cytotoxic serine protease C antibody
    • Cytotoxic T lymphocyte associated serine esterase 1 antibody
    • Cytotoxic T lymphocyte proteinase antibody
    • Cytotoxic T-lymphocyte proteinase antibody
    • EC 3.4.21.- antibody
    • GRAH_HUMAN antibody
    • Granzyme H (cathepsin G-like 2, protein h-CCPX) antibody
    • Granzyme H antibody
    • GZMH antibody
    • Protein h CCPX antibody
    see all

Anti-Granzyme H antibody images

  • Anti-Granzyme H antibody (ab89607) at 1 µg/ml + Human spleen tissue lysate at 50 µg

    Predicted band size : 27 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-Granzyme H antibody (ab89607) at 1 µg/ml

    Lane 1 : GZMH transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 27 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 33 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Granzyme H antibody (ab89607)

ab89607 has not yet been referenced specifically in any publications.

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