For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Goat polyclonal to GRB7
HumanPredicted to work with:
Synthetic peptide: ELDLSPPHLSSSPE, corresponding to amino acids 2-15 of Human GRB 7.
Principal Names - GRB7; growth factor receptor-bound protein 7
Official Gene Symbol - GRB7
GenBank Accession Number – NP_005301
LocusLink ID - 2886
Gene Ontology terms - oncogenesis; SH3/SH2 adaptor protein; EGF receptor signalling pathway
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
Concentration information loading...
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1 - 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2.
Belongs to the GRB7/10/14 family.
Contains 1 PH domain.
Contains 1 Ras-associating domain.
Contains 1 SH2 domain.
Phosphorylated on tyrosine residues.
Information by UniProt
- B47 antibody
- Epidermal growth factor receptor GRB 7 antibody
- Epidermal growth factor receptor GRB-7 antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"