Overview

  • Product nameAnti-GRF2 antibody
    See all GRF2 primary antibodies
  • Description
    Rabbit polyclonal to GRF2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human GRF2.

  • Positive control
    • Human breast carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111061 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionGuanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.
  • Tissue specificityUbiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
  • Sequence similaritiesContains 1 N-terminal Ras-GEF domain.
    Contains 1 Ras-GEF domain.
  • Information by UniProt
  • Database links
  • FormIt localizes to cytoplasm and endosomes.
  • Alternative names
    • C3G antibody
    • C3G protein antibody
    • CRK SH3 binding GNRP antibody
    • CRK SH3-binding GNRP antibody
    • DKFZp781P1719 antibody
    • GRF 2 antibody
    • GRF2 antibody
    • Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody
    • Guanine nucleotide releasing factor 2 antibody
    • Guanine nucleotide-releasing factor 2 antibody
    • OTTHUMP00000064558 antibody
    • Protein C3G antibody
    • Rap guanine nucleotide exchange factor (GEF) 1 antibody
    • Rap guanine nucleotide exchange factor 1 antibody
    • RAPGEF 1 antibody
    • RAPGEF1 antibody
    • RPGF1_HUMAN antibody
    see all

Anti-GRF2 antibody images

  • ab111061 at 1/50 dilution staining GRF2 in paraffin-embedded Human Breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

References for Anti-GRF2 antibody (ab111061)

ab111061 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"