• Product name
  • Description
    Mouse polyclonal to GRHL2
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human protein (NP_079191.1)

  • Positive control
    • A431 cell lysate Transfected 293T cell lysate HeLa cells



Our Abpromise guarantee covers the use of ab88631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 71 kDa.
ICC/IF Use a concentration of 10 µg/ml.


  • Function
    May function as a transcription factor.
  • Tissue specificity
    Highly expressed in placenta, prostate, brain and kidney. Lower-level expression in a variety of epithelial tissues such as thymus, kidney, lung, salivary gland, mammary gland and digestive tract. Expressed in the cochlear.
  • Involvement in disease
    Defects in GRHL2 are the cause of deafness autosomal dominant type 28 (DFNA28) [MIM:608641]. DFNA28 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA28 is characterized by mild to moderate hearing loss across most frequencies that progressed to severe loss in the higher frequencies by the fifth decade. Age at onset varied, with the earliest case documented at 7 years of age.
  • Sequence similarities
    Belongs to the grh/CP2 family. Grainyhead subfamily.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • BOM antibody
    • Brother of mammalian grainyhead antibody
    • Deafness autosomal dominant 28 antibody
    • DFNA28 antibody
    • ECTDS antibody
    • FLJ11172 antibody
    • FLJ13782 antibody
    • Grainyhead like 2 (Drosophila) antibody
    • Grainyhead like 2 antibody
    • Grainyhead like protein 2 homolog antibody
    • Grainyhead like transcription factor 2 antibody
    • Grainyhead-like protein 2 homolog antibody
    • GRHL 2 antibody
    • GRHL2 antibody
    • GRHL2_HUMAN antibody
    • MGC149294 antibody
    • MGC149295 antibody
    • RGD1561191 antibody
    • TFCP2L3 antibody
    • Transcription factor CP2 like 3 antibody
    • Transcription factor CP2-like 3 antibody
    see all

Anti-GRHL2 antibody images

  • Anti-GRHL2 antibody (ab88631) at 1 µg/ml + A431 cell lysate at 50 µg/ml

    Predicted band size : 71 kDa
  • All lanes : Anti-GRHL2 antibody (ab88631) at 1 µg/ml

    Lane 1 : GRHL2-transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 71 kDa
    Observed band size : 69 kDa (why is the actual band size different from the predicted?)
  • Immunofluorescence analysis of HeLa cells using ab88631 at a dilution of 10 µg/ml followed by fluorescein conjugated secondary antibody.

References for Anti-GRHL2 antibody (ab88631)

ab88631 has not yet been referenced specifically in any publications.

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