Overview

  • Product nameAnti-GRIK1 antibody
    See all GRIK1 primary antibodies
  • Description
    Rabbit polyclonal to GRIK1
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to 16 internal sequence amino acids of Human GRIK1.

  • Positive control
    • Human Adrenal tissue; Rat brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 104 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionIonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
  • Tissue specificityMost abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
  • Sequence similaritiesBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily.
  • Cellular localizationCell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EAA3 antibody
    • EEA3 antibody
    • Excitatory amino acid receptor 3 antibody
    • GLR5 antibody
    • GluR-5 antibody
    • GluR5 antibody
    • GluR6 antibody
    • GluR7 antibody
    • Glutamate receptor 5 antibody
    • Glutamate receptor antibody
    • Glutamate receptor ionotropic kainate 1 antibody
    • GRIK1 antibody
    • GRIK1_HUMAN antibody
    • Human glutamate receptor GLUR5 antibody
    • ionotropic kainate 1 antibody
    • OTTHUMP00000096569 antibody
    see all

Anti-GRIK1 antibody images

  • ab118891 at 5 µg/ml staining GRIK1 in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Lane 1 : Anti-GRIK1 antibody (ab118891) at 0.5 µg/ml
    Lane 2 : Anti-GRIK1 antibody (ab118891) at 1 µg/ml

    Lane 1 : Rat Brain Tissue Lysate
    Lane 2 : Rat Brain Tissue Lysate


    Predicted band size : 104 kDa

References for Anti-GRIK1 antibody (ab118891)

ab118891 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118891.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"