Overview

  • Product name
  • Description
    Rabbit polyclonal to GRIK5
  • Specificity
    ab67408 does not cross-react with GRIK4.
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid synthetic peptide from near the carboxy terminus of human GRIK5.

  • Positive control
    • Human brain tissue and brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab67408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 109 kDa).
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK5 subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EAA 2 antibody
    • EAA2 antibody
    • Excitatory amino acid receptor 2 antibody
    • GluK5 antibody
    • GluRgamma2 antibody
    • Glutamate receptor antibody
    • Glutamate receptor KA 2 antibody
    • Glutamate receptor KA-2 antibody
    • Glutamate receptor KA2 antibody
    • Glutamate receptor, ionotropic kainate 5 [Precursor] antibody
    • Glutamate receptor, ionotropic, kainate 5 (gamma 2) antibody
    • Glutamate receptor, ionotropic, kainate 5 antibody
    • GRIK 2 antibody
    • GRIK 5 antibody
    • GRIK2 antibody
    • Grik5 antibody
    • GRIK5_HUMAN antibody
    • iGlu5 antibody
    • ionotropic kainate 5 antibody
    • KA2 antibody
    • MGC118086 antibody
    see all

Anti-GRIK5 antibody images

  • Lane 1 : Anti-GRIK5 antibody (ab67408) at 0.5 µg/ml
    Lane 2 : Anti-GRIK5 antibody (ab67408) at 1 µg/ml
    Lane 3 : Anti-GRIK5 antibody (ab67408) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate
    Lane 3 : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 109 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
  • ab67408 at 2.5µg/ml staining of GRIK5 in human brain tissue by IHC-P.
  • Immunofluorescence of Grik5 in Human Brain cells using ab67408 at 20 ug/ml.

References for Anti-GRIK5 antibody (ab67408)

This product has been referenced in:
  • Zhu Z  et al. Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation. Sci Rep 6:19069 (2016). Read more (PubMed: 26753906) »
  • Funk JA  et al. Characterization of Renal Toxicity in Mice Administered the Marine Biotoxin Domoic Acid. J Am Soc Nephrol N/A:N/A (2014). Read more (PubMed: 24511141) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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