Overview

  • Product name
    Anti-GRK6 antibody [EPR2046(2)]
    See all GRK6 primary antibodies
  • Description
    Rabbit monoclonal [EPR2046(2)] to GRK6
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A synthetic peptide corresponding to residues in human GRK6.

  • Positive control
    • U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab109302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
ICC/IF 1/250 - 1/500.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function
      Specifically phosphorylates the activated forms of G protein-coupled receptors.
    • Tissue specificity
      Widely expressed.
    • Sequence similarities
      Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
      Contains 1 RGS domain.
    • Post-translational
      modifications
      It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Form
      There are 2 isoforms produced by alternative splicing.
    • Alternative names
      • FLJ32135 antibody
      • G protein coupled receptor kinase 6 antibody
      • G protein coupled receptor kinase GRK6 antibody
      • G protein-coupled receptor kinase 6 antibody
      • G protein-coupled receptor kinase GRK6 antibody
      • Gprk6 antibody
      • Grk6 antibody
      • GRK6_HUMAN antibody
      see all

    Images

    • All lanes : Anti-GRK6 antibody [EPR2046(2)] (ab109302) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 66 kDa

    References

    This product has been referenced in:
    • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . Read more (PubMed: 23576548) »

    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab109302.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up