Overview

  • Product nameAnti-GRK6 antibody [EPR2046(2)]
    See all GRK6 primary antibodies
  • Description
    Rabbit monoclonal [EPR2046(2)] to GRK6
  • Tested applicationsSuitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A synthetic peptide corresponding to residues in human GRK6.

  • Positive control
    • U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab109302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
ICC/IF 1/250 - 1/500.
  • Application notesIs unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • FunctionSpecifically phosphorylates the activated forms of G protein-coupled receptors.
    • Tissue specificityWidely expressed.
    • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
      Contains 1 RGS domain.
    • Post-translational
      modifications
      It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • FormThere are 2 isoforms produced by alternative splicing.
    • Alternative names
      • FLJ32135 antibody
      • G protein coupled receptor kinase 6 antibody
      • G protein coupled receptor kinase GRK6 antibody
      • G protein-coupled receptor kinase 6 antibody
      • G protein-coupled receptor kinase GRK6 antibody
      • Gprk6 antibody
      • Grk6 antibody
      • GRK6_HUMAN antibody
      see all

    Anti-GRK6 antibody [EPR2046(2)] images

    • All lanes : Anti-GRK6 antibody [EPR2046(2)] (ab109302) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 66 kDa

    References for Anti-GRK6 antibody [EPR2046(2)] (ab109302)

    This product has been referenced in:
    • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . Read more (PubMed: 23576548) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109302.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"