Overview

  • Product name
    Anti-GRO beta antibody
    See all CXCL2 primary antibodies
  • Description
    Goat polyclonal to GRO beta
  • Specificity
    In immunoblotting and ELISA, this antibody exhibits greater than 50 % crossreactivity with recombinant rat CINC1, rat CINC2 beta, recombinant mouse KC, and mouse MIP2. Also, less than 25 % cross-reactivity is exhibited using this antibody with recombinant human IL-8, human GRO alpha, human GRO beta, and human GRO gamma.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Purified recombinant rat CINC2 alpha expressed in E. coli.

  • General notes
    Endotoxin: <10 ng/mg antibody determined by the LAL method.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Affinity isolated antigen specific antibody is obtained from goat anti-CINC2 alpha antiserum by immunospecific purification which removes essentially all goat serum proteins, including immunoglobulins, which do not specifically bind to the peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab10366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA: Use at a concentration of 0.5 - 1 µg/ml. The detection limit is approximately 0.06 ng recombinant rat CINC2 alpha per well.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 7.6 kDa.
    The detection limit of recombinant rat CINC2 alpha is approximately 2 ng/lane and 20 ng/lane under nonreducing and reducing conditions, respectively.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
    • Sequence similarities
      Belongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications
      The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C-X-C motif chemokine 2 antibody
      • Chemokine (C X C motif) ligand 2 antibody
      • Chemokine, CXC motif, ligand 2 antibody
      • CINC 2a antibody
      • CINC2a antibody
      • CINC3 antibody
      • CXC chemokine antibody
      • CXCL 2 antibody
      • Cxcl2 antibody
      • CXCL2_HUMAN antibody
      • Cytokine-induced neutrophil chemoattractant 3 antibody
      • GRO 2 antibody
      • GRO b antibody
      • GRO protein, beta antibody
      • Gro-beta antibody
      • GRO-beta(5-73) antibody
      • GRO-beta-T antibody
      • GRO2 antibody
      • GRO2 oncogene antibody
      • GROb antibody
      • GRObeta antibody
      • Growth regulated protein beta antibody
      • Growth-regulated protein beta antibody
      • GROX antibody
      • Hematopoietic synergistic factor antibody
      • HSF antibody
      • Macrophage inflammatory protein 2 alpha antibody
      • Macrophage inflammatory protein 2 antibody
      • Macrophage inflammatory protein 2-alpha antibody
      • Melanoma growth stimulatory activity beta antibody
      • MGSA b antibody
      • MGSA beta antibody
      • MIP 2 antibody
      • MIP 2a antibody
      • MIP2 alpha antibody
      • MIP2 antibody
      • MIP2-alpha antibody
      • MIP2A antibody
      • MIP2alpha antibody
      • SB-251353 antibody
      • SCYB 2 antibody
      • Scyb antibody
      • SCYB2 antibody
      • Small inducible cytokine subfamily B, member 2 antibody
      see all

    References for Anti-GRO beta antibody (ab10366)

    ab10366 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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