Overview

  • Product nameGSK 4716
  • Description
    Selective ERRβγ agonist
  • Biological descriptionSelective ERRβ/γ agonist. Displays selectivity for ERRβ/γ over ERRα/β as well as other classical estrogen receptors. ERRβ is transiently induced and ERRγ is dramatically induced in vitro. Cell-permeable. Increases glucocorticoid receptor (GR) and 11beta-hydroxysteroid dehydrogenase type 1 mRNA in vitro.
  • Purity> 99%

Properties

    References for GSK 4716 (ab120826)

    This product has been referenced in:
    • Wang SC  et al. An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells. Mol Cell Endocrinol 315:146-52 (2010). Read more (PubMed: 19631715) »
    • Kim Y  et al. Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach. J Comb Chem 11:928-37 (0). Read more (PubMed: 19746993) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120826.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"