Validated using a knockout cell line

Anti-GSK3 beta antibody [Y174] (ab32391)

Publishing research using ab32391? Please let us know so that we can cite the reference in this datasheet.

ab32391 has been referenced in 28 publications.

  • Yang R  et al. Knockout of the placenta specific 8 gene radiosensitizes nasopharyngeal carcinoma cells by activating the PI3K/AKT/GSK3ß pathway. Am J Transl Res 10:455-464 (2018). PubMed: 29511439
  • He F  et al. Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells. Mol Med Rep 17:4973-4980 (2018). PubMed: 29393470
  • Dewi FRP  et al. Colorectal cancer cells require glycogen synthase kinase-3ß for sustaining mitosis via translocated promoter region (TPR)-dynein interaction. Oncotarget 9:13337-13352 (2018). PubMed: 29568361
  • Majumder P  et al. Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario. Dis Model Mech 10:655-669 (2017). PubMed: 28360125
  • Mao XW  et al. CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/ß-catenin signaling pathway. Oncotarget 8:77241-77253 (2017). PubMed: 29100384
  • Luo J  et al. Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-?B signaling pathwaysin vitro. Exp Ther Med 14:3623-3631 (2017). PubMed: 29042957
  • Zhang XL  et al. Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity. Exp Ther Med 14:3856-3861 (2017). PubMed: 29042992
  • Zhou D  et al. Microarray data re-annotation reveals specific lncRNAs and their potential functions in non-small cell lung cancer subtypes. Mol Med Rep 16:5129-5136 (2017). PubMed: 28849055
  • Yu N  et al. Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice. PLoS One 12:e0168980 (2017). Mouse . PubMed: 28045971
  • Kong LY  et al. In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/ß-catenin signaling pathway. Oncotarget 8:15507-15519 (2017). WB ; Human . PubMed: 28099945
  • Tian Y  et al. Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways. Front Mol Neurosci 10:190 (2017). WB ; Mouse . PubMed: 28663724
  • Li Y  et al. Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice. Oncotarget 7:60446-60460 (2016). WB ; Mouse . PubMed: 27507058
  • Guo J  et al. Glycogen synthase kinase-3ß is required for epithelial-mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions. Mol Med Rep 14:4091-4098 (2016). WB ; Mouse . PubMed: 27748847
  • Jiang S  et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep 14:1891-900 (2016). WB ; Human . PubMed: 27432616
  • Qu F  et al. MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/ß-catenin pathway. Oncol Lett 11:1592-1596 (2016). WB ; Human . PubMed: 26893786
  • Sun J  et al. Astragaloside IV protects new born rats from anesthesia-induced apoptosis in the developing brain. Exp Ther Med 12:1829-1835 (2016). PubMed: 27588101
  • Lin Y  et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3ß/CTNNB1 signaling pathway. Sci Rep 5:8997 (2015). PubMed: 25757764
  • Su H  et al. FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R. J Transl Med 13:104 (2015). PubMed: 25888911
  • Huang HJ  et al. Administration of NaHS Attenuates Footshock-Induced Pathologies and Emotional and Cognitive Dysfunction in Triple Transgenic Alzheimer's Mice. Front Behav Neurosci 9:312 (2015). WB ; Mouse . PubMed: 26635562
  • Das I  et al. Heat Shock Protein 90 Positively Regulates Chikungunya Virus Replication by Stabilizing Viral Non-Structural Protein nsP2 during Infection. PLoS One 9:e100531 (2014). WB ; African green monkey . PubMed: 24959709
  • Gao B  et al. Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway. PLoS One 9:e99137 (2014). Mouse . PubMed: 24918446
  • Lang M  et al. Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling. Mol Cancer 12:41 (2013). WB, ICC ; Mouse . PubMed: 23668310
  • Olsen AK  et al. Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells. Carcinogenesis 34:1361-9 (2013). Human . PubMed: 23393221
  • Wang WY  et al. A Gene Expression Signature of Epithelial Tubulogenesis and a Role for ASPM in Pancreatic Tumor Progression. Gastroenterology 145:1110-20 (2013). WB ; Human . PubMed: 23896173
  • John JK  et al. GSK3ß Inhibition Blocks Melanoma Cell/Host Interactions by Downregulating N-Cadherin Expression and Decreasing FAK Phosphorylation. J Invest Dermatol : (2012). PubMed: 22810307
  • Ha GH  et al. Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation. Cell Death Differ 19:321-32 (2012). PubMed: 21818122
  • Juhlin CC  et al. Loss of expression for the Wnt pathway components adenomatous polyposis coli and glycogen synthase kinase 3-beta in parathyroid carcinomas. Int J Oncol 34:481-92 (2009). IHC-P ; Human . PubMed: 19148484
  • Miyashita K  et al. Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma. Clin Cancer Res 15:887-97 (2009). WB, IHC-P ; Human . PubMed: 19188159


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