Overview

  • Product name
    Anti-GTF2IRD2 antibody
  • Description
    Rabbit polyclonal to GTF2IRD2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 820-850 of Human GTF2IRD2

  • Positive control
    • K562 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 107 kDa.

Target

  • Relevance
    GTF2IRD2 N-terminal half contains a leucine zipper motif, followed by 2 helix-loop-helix motifs (I repeats) that share homology with the TFII-I family of transcription factors. The C-terminal half of GTF2IRD2A contains a CHARLIE8 transposable element-like sequence, including 3 transposase-related domains that may be functional, and a BED zinc finger DNA-binding motif. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. There are six different isoforms, generated by alternative splicing.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • FLJ21423 antibody
    • FLJ37938 antibody
    • FP630 antibody
    • general transcription factor II i repeat domain 2 alpha antibody
    • general transcription factor II I repeat domain-containing protein 2A antibody
    • GTF2I repeat domain containing 2 antibody
    • GTF2I repeat domain containing protein 2A antibody
    • GTF2IRD2 alpha antibody
    • GTF2IRD2A antibody
    • MGC75203 antibody
    • Transcription factor GTF2IRD2 alpha antibody
    • transcription factor GTF2IRD2 antibody
    see all

Images

  • Anti-GTF2IRD2 antibody (ab103946) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 107 kDa

References

ab103946 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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