Overview

  • Product nameAnti-GTF2IRD2 antibody
    See all GTF2IRD2 primary antibodies
  • Description
    Mouse polyclonal to GTF2IRD2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1 - 498 of Human GTF2IRD2 isoform 3 (AAH67859)

  • Positive control
    • HeLa nuclear extracts

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab88802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at an assay dependent dilution. Predicted molecular weight: 107 kDa (isoform 1).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceGTF2IRD2 N-terminal half contains a leucine zipper motif, followed by 2 helix-loop-helix motifs (I repeats) that share homology with the TFII-I family of transcription factors. The C-terminal half of GTF2IRD2A contains a CHARLIE8 transposable element-like sequence, including 3 transposase-related domains that may be functional, and a BED zinc finger DNA-binding motif. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. There are six different isoforms, generated by alternative splicing.
    • Cellular localizationNuclear
    • Database links
    • Alternative names
      • FLJ21423 antibody
      • FLJ37938 antibody
      • FP630 antibody
      • general transcription factor II i repeat domain 2 alpha antibody
      • general transcription factor II I repeat domain-containing protein 2A antibody
      • GTF2I repeat domain containing 2 antibody
      • GTF2I repeat domain containing protein 2A antibody
      • GTF2IRD2 alpha antibody
      • GTF2IRD2A antibody
      • MGC75203 antibody
      • Transcription factor GTF2IRD2 alpha antibody
      • transcription factor GTF2IRD2 antibody
      see all

    Anti-GTF2IRD2 antibody images

    • Anti-GTF2IRD2 antibody (ab88802) at 1 µg/ml + HeLa nuclear extracts at 50 µg

      Predicted band size : 107 kDa
    • All lanes : Anti-GTF2IRD2 antibody (ab88802) at 1 µg/ml

      Lane 1 : GTF2IRD2 (isoform 3)-transfected 293T cell lysate
      Lane 2 : non transfected lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 107 kDa

    References for Anti-GTF2IRD2 antibody (ab88802)

    ab88802 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"