Anti-GTF3C4 antibody - N-terminal (ab170386)

Overview

  • Product name
    Anti-GTF3C4 antibody - N-terminal
    See all GTF3C4 primary antibodies
  • Description
    Rabbit polyclonal to GTF3C4 - N-terminal
  • Tested applications
    Suitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human GTF3C4 aa 221-252 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9UKN8

  • Positive control
    • HeLa cells; NIH-3T3 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab170386 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 92 kDa.
Flow Cyt 1/10 - 1/50. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
  • Sequence similarities
    Belongs to the TFIIIC subunit 4 family.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 2.3.1.48 antibody
    • FLJ21002 antibody
    • General transcription factor 3C 4 antibody
    • General transcription factor 3C polypeptide 4 antibody
    • General transcription factor IIIC, polypeptide 4, 90kDa antibody
    • GTF3C4 antibody
    • KAT12 antibody
    • MGC138450 antibody
    • OTTHUMP00000022434 antibody
    • TF3C delta antibody
    • TF3C-delta antibody
    • TF3C4_HUMAN antibody
    • TFIII90 antibody
    • TFIIIC 90 kDa subunit antibody
    • TFiiiC2 90 antibody
    • TFIIIC290 antibody
    • TFIIIC90 antibody
    • TFIIICdelta antibody
    • Transcription factor IIIC 90 kDa subunit antibody
    • Transcription factor IIIC subunit delta antibody
    see all

Images

  • Flow cytometric analysis of HeLa cells labeling GTF3C4 with ab170386 at 1/10 dilution (right histogram) compared to negative control cells (left histogram). FITC-conjugated goat anti-rabbit secondary antibodies were used for the analysis.

  • Anti-GTF3C4 antibody - N-terminal (ab170386) at 1/100 dilution + NIH-3T3 cell lysate at 35 µg

    Predicted band size : 92 kDa

References

ab170386 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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