Anti-Guanylate Cyclase antibody (ab14438)

Overview

  • Product nameAnti-Guanylate Cyclase antibody
    See all Guanylate Cyclase primary antibodies
  • Description
    Rabbit polyclonal to Guanylate Cyclase
  • SpecificityAb14438 recognises synthetic intestinal guanylate cyclase.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    EFTEEEAKVPEIL

    , corresponding to amino acids 421-433 of Rat Guanylate Cyclase.

Properties

Applications

Our Abpromise guarantee covers the use of ab14438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 119 kDa.

Target

  • RelevanceGuanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • GC SB2 antibody
    • GCS beta 2 antibody
    • Guanylate cyclase 1 soluble beta 2 antibody
    • GUCY1B2 antibody

References for Anti-Guanylate Cyclase antibody (ab14438)

ab14438 has not yet been referenced specifically in any publications.

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Thank you very much for contacting us with your question.

This antibody is provided as unpurified, whole antiserum, and so the concentration of the specific IgG can not be measured in this solution. We estimate that the IgG concentration is b...

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Thank you for your enquiry and patience. Ab14438 was tested using synthetic intestinal guanylate cyclase. But since guanylate cyclase is known to be expressed in the kidney and liver, I would suggest using rat kidney or liver lysate for a control. I...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"