Overview

  • Product nameAnti-GUCY2C antibody
    See all GUCY2C primary antibodies
  • Description
    Rabbit polyclonal to GUCY2C
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen: EVRGETYLKG RGNETTYWLT GMKDQKFNLP TPPTVENQQR LQAEFSDMIA NSLQKRQAAG IRSQKPRRVA SYKKGTLEYL QLNTTD, corresponding to amino acids 982-1067 of Human GUCY2C according to P25092.

  • Positive control
    • Human lateral ventricle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionReceptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.
  • Sequence similaritiesBelongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 1 guanylate cyclase domain.
    Contains 1 protein kinase domain.
  • DomainThe protein kinase domain is predicted to be catalytically inactive.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GC-C antibody
    • Guanylyl cyclase C antibody
    • GUC2C antibody
    • GUC2C_HUMAN antibody
    • GUCY2C antibody
    • Heat stable enterotoxin receptor antibody
    • Heat-stable enterotoxin receptor antibody
    • hSTAR antibody
    • Intestinal guanylate cyclase antibody
    • STA receptor antibody
    see all

Anti-GUCY2C antibody images

  • ab122404, at a 1/550 dilution, staining GUCY2C in neuronal cells of paraffin-embedded Human lateral ventricle tissue by immunohistochemistry.

References for Anti-GUCY2C antibody (ab122404)

ab122404 has not yet been referenced specifically in any publications.

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