Overview

  • Product nameAnti-H Cadherin antibody
    See all H Cadherin primary antibodies
  • Description
    Rabbit polyclonal to H Cadherin
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to 15 amino acids from near the N terminus of Human H Cadherin.

  • Positive control
    • Human Heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab116214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 78 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionCadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
  • Tissue specificityHighly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord.
  • Sequence similaritiesContains 5 cadherin domains.
  • Developmental stageExpressed at higher levels in adult brain than in developing brain.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAD13_HUMAN antibody
    • Cadherin-13 antibody
    • CDH13 antibody
    • CDHH antibody
    • H-cadherin antibody
    • Heart cadherin antibody
    • P105 antibody
    • T cad antibody
    • T Cadherin antibody
    • T-cad antibody
    • T-cadherin antibody
    • Truncated cadherin antibody
    see all

Anti-H Cadherin antibody images

  • ab116214, at 5 µg/ml, staining H Cadherin in Formalin-fixed, Paraffin-embedded Human heart tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-H Cadherin antibody (ab116214)

ab116214 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"