Overview

  • Product name
  • Description
    Rabbit polyclonal to HAAO
  • Tested applications
    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, 17 aa from near the N-terminus of Human HAAO (NP_036337).

  • Positive control
    • Mouse liver tissue lysate, Human liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab106436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 33 kDa.

Target

  • Function
    Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
  • Pathway
    Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.
  • Sequence similarities
    Belongs to the 3-HAO family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Form
    There are 2 isoforms produced by alternative splicing.
  • Alternative names
    • 3 HAO antibody
    • 3 hydroxyanthranilate 3 4 dioxygenase antibody
    • 3 hydroxyanthranilate dioxygenase antibody
    • 3 hydroxyanthranilate oxygenase antibody
    • 3 hydroxyanthranilic acid dioxygenase antibody
    • 3-HAO antibody
    • 3-hydroxyanthranilate 3,4-dioxygenase antibody
    • 3-hydroxyanthranilate oxygenase antibody
    • 3-hydroxyanthranilic acid dioxygenase antibody
    • 3HAO_HUMAN antibody
    • haao antibody
    • HAD antibody
    • HAO antibody
    see all

Images

  • Anti-HAAO antibody (ab106436) at 1 µg/ml + Mouse liver tissue lysate at 15 µg

    Predicted band size : 33 kDa
  • ab106436, at 2.5 ug/ml, staining HAAO in human liver tissue by immunohistochemistry.
  • Immunofluorescence of HAAO in Human Liver cells using ab106436 at 20 ug/ml.

References

This product has been referenced in:
  • Ahmad Y  et al. The proteome of Hypobaric Induced Hypoxic Lung: Insights from Temporal Proteomic Profiling for Biomarker Discovery. Sci Rep 5:10681 (2015). WB . Read more (PubMed: 26022216) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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