Anti-HADHB antibody (ab103174)

Overview

• Product name
  Anti-HADHB antibody
  See all HADHB primary antibodies
• Description
  Rabbit polyclonal to HADHB
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide corresponding to a region within C terminal amino acids 321-351 of Human HADHB, conjugated to KLH.

• Positive control
  • Jurkat cell line lysate

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage buffer
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Signal Transduction
  • Metabolism
  • Mitochondrial

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• Pathway
  Lipid metabolism; fatty acid beta-oxidation.
• Involvement in disease
  Defects in HADHB are a cause of trifunctional protein deficiency (TFP deficiency) [MIM:609015]. The clinical manifestations are very variable and include hypoglycemia, cardiomyopathy and sudden death. Phenotypes with mainly hepatic and neuromyopathic involvement can also be distinguished. Biochemically, TFP deficiency is defined by the loss of all three enzyme activities of the TFP complex.
• Sequence similarities
  Belongs to the thiolase family.
• Cellular localization
  Mitochondrion.

• Target information above from: UniProt accession P55084 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 3032 Human
  • Omim: 143450 Human
  • SwissProt: P55084 Human
  • Unigene: 515848 Human
• Alternative names
  • 2 enoyl Coenzyme A (CoA) hydratase beta subunit antibody
  • 3 ketoacyl Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein beta subunit antibody
  • 3 ketoacyl Coenzyme A thiolase antibody

  • 3 ketoacyl Coenzyme A thiolase of mitochondrial trifunctional protein beta subunit antibody
  • 3-ketoacyl-CoA thiolase antibody
  • Acetyl CoA acyltransferase antibody
  • Acetyl-CoA acyltransferase antibody
  • Beta ketothiolase antibody
  • Beta-ketothiolase antibody
  • ECHB antibody
  • ECHB_HUMAN antibody
  • HADH antibody
  • Hadhb antibody
  • Hydroxyacyl CoA dehydrogenase/3 ketoacyl CoA thiolase/enoyl CoA hydratase (trifunctional protein), beta subunit antibody
  • Hydroxyacyl Coenzyme A (CoA) dehydrogenase beta subunit antibody
  • Hydroxyacyl Coenzyme A dehydrogenase antibody
  • Hydroxyacyl Coenzyme A dehydrogenase beta subunit antibody
  • Hydroxyacyl Coenzyme A dehydrogenase/3 ketoacyl Coenzyme A thiolase/enoyl Coenzyme A hydratase (trifunctional protein) beta subunit antibody
  • MGC87480 antibody
  • Mitochondrial trifunctional enzyme beta subunit antibody
  • Mitochondrial trifunctional protein beta subunit antibody
  • MSTP 029 antibody
  • MSTP029 antibody
  • MTPB antibody
  • TP beta antibody
  • TP-beta antibody
  • TPbeta antibody
  • Trifunctional enzyme subunit beta antibody
  • Trifunctional enzyme subunit beta mitochondrial antibody
  • Trifunctional protein antibody

  see all

Protocols

• Western blot protocols