Recombinant
RabMAb

Anti-HARS antibody [EPR9451] (ab155087)

Overview

  • Product name
    Anti-HARS antibody [EPR9451]
    See all HARS primary antibodies
  • Description
    Rabbit monoclonal [EPR9451] to HARS
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, coresponding to residues in Human HARS (UniProt: P12081).

  • Positive control
    • HeLa, K562 and Human fetal lung lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 57 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Tissue specificity
      Brain, heart, liver and kidney.
    • Involvement in disease
      Defects in HARS are a cause of Usher syndrome type 3B (USH3B) [MIM:614504]. USH3B is a syndrome characterized by progressive vision and hearing loss during early childhood. Some patients have the so-called 'Charles Bonnet syndrome,' involving decreased visual acuity and vivid visual hallucinations. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH3 is characterized by postlingual, progressive hearing loss, variable vestibular dysfunction, and onset of retinitis pigmentosa symptoms, including nyctalopia, constriction of the visual fields, and loss of central visual acuity, usually by the second decade of life.
    • Sequence similarities
      Belongs to the class-II aminoacyl-tRNA synthetase family.
      Contains 1 WHEP-TRS domain.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • cytoplasmic antibody
      • EC 6.1.1.21 antibody
      • FLJ20491 antibody
      • HARS antibody
      • HisRS antibody
      • Histidine tRNA ligase, cytoplasmic antibody
      • histidine translase antibody
      • Histidine tRNA ligase antibody
      • Histidine--tRNA ligase antibody
      • Histidyl tRNA synthetase antibody
      • Histidyl-tRNA synthetase antibody
      • HRS antibody
      • Human histidyl tRNA synthetase homolog (HO3) mRNA complete cds antibody
      • SYHC_HUMAN antibody
      • USH3B antibody
      see all

    Images

    • All lanes : Anti-HARS antibody [EPR9451] (ab155087) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : K562 cell lysate
      Lane 3 : Human fetal lung lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 57 kDa

    References

    ab155087 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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