Overview

  • Product nameAnti-HB9/HLXB9 antibodySee all HB9/HLXB9 primary antibodies ...
  • Description
    Sheep polyclonal to HB9/HLXB9
  • SpecificityThe antibody is specific for HB9 in Human and Mouse. This has been confirmed by Immunohistochemical analysis of Normal Term and First Trimester Human Placenta as well as western blot analysis of mouse Neuroblastoma and Spinal Cord cells (NSC-34).
  • Tested applicationsIHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide: H-

    APADRLRAESPSPPRLLAAHC

    -NH2 conjugated to Blue Carrier Protein, corresponding to amino acids 68-88 of Human HB9/HLXB9

  • Positive control
    • Normal Term and First Trimester Human Placenta and Mouse Neuroblastoma and Spinal Cord cells (NSC-34).

Properties

Applications

Our Abpromise guarantee covers the use of ab64058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent dilution.
ELISA 1/200 - 1/2600.
WB 1/400. Predicted molecular weight: 41 kDa.

Target

  • FunctionPutative transcription factor involved in pancreas development and function.
  • Tissue specificityExpressed in lymphoid and pancreatic tissues.
  • Involvement in diseaseDefects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
  • Sequence similaritiesContains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HB 9 antibody
    • HB9 antibody
    • HLXB 9 antibody
    • HLXB9 antibody
    • Homeo box HB9 antibody
    • Homeobox HB9 antibody
    • Homeobox protein HB9 antibody
    • HOXHB9 antibody
    • MNX1 antibody
    • MNX1_HUMAN antibody
    • Motor neuron and pancreas homeobox protein 1 antibody
    • Sacral agenesis autosomal dominant (Currarino triad) antibody
    • SCRA 1 antibody
    • SCRA1 antibody
    see all

References for Anti-HB9/HLXB9 antibody (ab64058)

ab64058 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Spinal cord at embryonic day e12.5)
Specification Spinal cord at embryonic day e12.5
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Username

Dr. Frederic Clotman

Verified customer

Submitted Apr 20 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"