Overview

  • Product name
  • Description
    Rabbit polyclonal to HB9/HLXB9
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide, corresponding to a portion of amino acids 330 - 380 of Mouse HB9/HLXB9 (NP_064328.2).

  • Positive control
    • WB: MOLT 4 cell lysate; IHC-P: Mouse pancreas tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab92606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notes
    IHC-P: Use at a concentration of 5 µg/ml.
    WB: Use at a concentration of 0.5 - 2.0 µg/ml. Predicted molecular weight: 41 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Putative transcription factor involved in pancreas development and function.
    • Tissue specificity
      Expressed in lymphoid and pancreatic tissues.
    • Involvement in disease
      Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
    • Sequence similarities
      Contains 1 homeobox DNA-binding domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • HB 9 antibody
      • HB9 antibody
      • HLXB 9 antibody
      • HLXB9 antibody
      • Homeo box HB9 antibody
      • Homeobox HB9 antibody
      • Homeobox protein HB9 antibody
      • HOXHB9 antibody
      • MNX1 antibody
      • MNX1_HUMAN antibody
      • Motor neuron and pancreas homeobox 1 antibody
      • Motor neuron and pancreas homeobox protein 1 antibody
      • Sacral agenesis autosomal dominant (Currarino triad) antibody
      • SCRA 1 antibody
      • SCRA1 antibody
      see all

    Images

    • Immunohistochemistry analysis of HB9/HLXB9 expression in formalin-fixed, paraffin-embedded Mouse pancreas tissue using: an isotype control (1) or ab92606 at 5µg/ml (2 and 3).
    • All lanes : Anti-HB9/HLXB9 antibody (ab92606) at 0.5 µg/ml

      Lane 1 : MOLT 4 cell lysate
      Lane 2 : MOLT 4 cell lysate with immunizing peptide

      Secondary
      HRP-conjugated Goat anti-Rabbit IgG

      Predicted band size : 41 kDa

    References

    This product has been referenced in:
    • Serre A  et al. Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev 21:539-53 (2012). Human . Read more (PubMed: 21561385) »

    See 1 Publication for this product

    Customer reviews and Q&As

    Thank you for contacting us. Each new batch of ab92606 is QC tested in WB on MOLT4 cell lysates. For ab20670, each batch is tested in IHC-Fr on E11.5 mouse embryonic brain. I hope this helps, please let me know if you need any additional information or...

    Read More

    Thank you for contacting Abcam.

    That is a perfectly acceptable range for short term storage.

    Please let me know if you have any questions.

    Abcam ships this product at approximately 2 - 8oC with ice packs. A Certificate of Compliance is available for each lot. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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