Overview

  • Product nameAnti-HBXIP antibody
    See all HBXIP primary antibodies
  • Description
    Rabbit polyclonal to HBXIP
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 43-92 (FVPLEAPLRS TPRSRQVTEA CGGEGRAVPL GSEPEWSVGG MEATLEQHLE) of Human HBXIP (NP_006393).

  • Positive control
    • COLO205 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 10 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionWhen complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
  • Tissue specificityHighly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
  • Sequence similaritiesBelongs to the HBXIP family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • HBV X interacting protein antibody
    • HBV X-interacting protein antibody
    • HBX interacting protein antibody
    • HBX-interacting protein antibody
    • hbxip antibody
    • HBXIP_HUMAN antibody
    • Hepatitis B virus X interacting protein antibody
    • Hepatitis B virus X-interacting protein antibody
    • LAMTOR5 antibody
    • Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody
    • MGC71071 antibody
    • Ragulator complex protein LAMTOR5 antibody
    • XIP antibody
    see all

Anti-HBXIP antibody images

  • Anti-HBXIP antibody (ab125410) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 10 kDa

References for Anti-HBXIP antibody (ab125410)

ab125410 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"