Overview

  • Product name
  • Description
    Mouse polyclonal to HBXIP
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human) with tag.

  • Positive control
    • Full length recombinant HBXIP with tag.

Properties

Applications

Our Abpromise guarantee covers the use of ab66258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution.
    WB: 1/1000 - 1/2500. Predicted molecular weight: 10 kDa.

    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
    • Tissue specificity
      Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
    • Sequence similarities
      Belongs to the HBXIP family.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • HBV X interacting protein antibody
      • HBV X-interacting protein antibody
      • HBX interacting protein antibody
      • HBX-interacting protein antibody
      • hbxip antibody
      • HBXIP_HUMAN antibody
      • Hepatitis B virus X interacting protein antibody
      • Hepatitis B virus X-interacting protein antibody
      • LAMTOR5 antibody
      • Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody
      • MGC71071 antibody
      • Ragulator complex protein LAMTOR5 antibody
      • XIP antibody
      see all

    Images



    • Predicted band size : 10 kDa

    References

    ab66258 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab66258.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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