Anti-HCC1 antibody (ab12326)

Overview

  • Product name
  • Description
    Rabbit polyclonal to HCC1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human HCC1 aa 480-530.
    (Peptide available as ab40426)

  • Positive control
    • Nuclear extract from HeLa cells.
  • General notes
    Centrifuge tube to remove product from lid.

Properties

Applications

Our Abpromise guarantee covers the use of ab12326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 59 kDa.

Target

  • Function
    Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
  • Tissue specificity
    Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.
  • Sequence similarities
    Belongs to the splicing factor SR family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization
    Nucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAPER alpha antibody
    • CAPER antibody
    • CAPERalpha antibody
    • CC1.3 antibody
    • Coactivator of activating protein 1 and estrogen receptors antibody
    • Coactivator of AP1 and ERs antibody
    • DKFZp781C0423 antibody
    • FLJ44170 antibody
    • HCC 1 antibody
    • Hepatocellular carcinoma protein 1 antibody
    • RBM 39 antibody
    • RBM39 antibody
    • RBM39_HUMAN antibody
    • RNA binding motif protein 39 antibody
    • RNA binding region (RNP1 RRM) containing 2 antibody
    • RNA binding region containing 2 antibody
    • RNA binding region containing protein 2 antibody
    • RNA-binding motif protein 39 antibody
    • RNA-binding protein 39 antibody
    • RNA-binding region-containing protein 2 antibody
    • RNPC 2 antibody
    • RNPC2 antibody
    • Splicing factor CC1.3 antibody
    • Splicing factor CC1.4 antibody
    • Splicing factor HCC 1 antibody
    • Splicing factor HCC1 antibody
    • Transcription coactivator CAPER antibody
    see all

Images

  • Detection of Human Caper by Western Blot. Samples: Nuclear extract (NE) from HeLa cells. Antibody: ab12326 used at 0.3 mcg/ml. Detection: Chemiluminescence with an exposure time of 5 minutes.

    Detection of Human Caper by Western Blot. Samples: Nuclear extract (NE) from HeLa cells. Antibody: ab12326 used at 0.3 mcg/ml. Detection: Chemiluminescence with an exposure time of 5 minutes.

References

ab12326 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Human Cell lysate - whole cell (HeLa, 293, U2OS)
Loading amount
30 µg
Specification
HeLa, 293, U2OS
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
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Verified customer

Submitted Jan 29 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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