Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab56596 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 1 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTranscriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
    • Tissue specificityWidely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.
    • Sequence similaritiesBelongs to the splicing factor SR family.
      Contains 3 RRM (RNA recognition motif) domains.
    • Cellular localizationNucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.
    • Information by UniProt
    • Database links
    • Alternative names
      • CAPER alpha antibody
      • CAPER antibody
      • CAPERalpha antibody
      • CC1.3 antibody
      • Coactivator of activating protein 1 and estrogen receptors antibody
      • Coactivator of AP1 and ERs antibody
      • DKFZp781C0423 antibody
      • FLJ44170 antibody
      • HCC 1 antibody
      • Hepatocellular carcinoma protein 1 antibody
      • RBM 39 antibody
      • RBM39 antibody
      • RBM39_HUMAN antibody
      • RNA binding motif protein 39 antibody
      • RNA binding region (RNP1 RRM) containing 2 antibody
      • RNA binding region containing 2 antibody
      • RNA binding region containing protein 2 antibody
      • RNA-binding motif protein 39 antibody
      • RNA-binding protein 39 antibody
      • RNA-binding region-containing protein 2 antibody
      • RNPC 2 antibody
      • RNPC2 antibody
      • Splicing factor CC1.3 antibody
      • Splicing factor CC1.4 antibody
      • Splicing factor HCC 1 antibody
      • Splicing factor HCC1 antibody
      • Transcription coactivator CAPER antibody
      see all

    Anti-HCC1 antibody images

    • HCC1 antibody (ab56596) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human endometrium.


    • Predicted band size : 59 kDa
      HCC1 antibody (ab56596) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-HCC1 antibody (ab56596)

    This product has been referenced in:
    • Chai Y  et al. Overexpression of HCC1/CAPERa may play a role in lung cancer carcinogenesis. Tumour Biol 35:6311-7 (2014). WB, ICC/IF ; Human . Read more (PubMed: 24643682) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab56596.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"