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Product Name
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hCG antibody [2092]
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See all hCG antibodies (17)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [2092] to hCG
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Reacts with
(species key)
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Hu
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Specificity
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This antibody reacts with high specificity to ß-HCG.
This antibody does not detect FSH or MSH
There is a slight reaction with LH
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Tested applications
(see key)
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ELISA, ICC/IF, IHC-Fr, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Cannot be used for RIA with radio-labeled antigen.
For tissue sections, dilute 1:5-1:25 with PBS
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Positive control
(see definition)
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Placenta
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Cellular localization
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Secreted
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Developmental Biology >> Reproduction >> Hormones
Cancer >> Tumor biomarkers >> Hormones
Cancer >> Growth factors >> Hormones
Signal Transduction >> Growth Factors/Hormones >> Hormones
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Relevance
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Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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2092
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Isotype
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IgG1
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Purity
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IgG fraction
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Storage buffer
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PBS with 1% BSA and 10mM sodium azide Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.020 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this hCG antibody [2092] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to hCG
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