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Products:Signal Transduction >> Growth Factors/Hormones >> Hormones
Overview
Product name
Anti-hCG antibody [2092]
See all hCG products (18) ...
Description
Mouse monoclonal [2092] to hCG
Specificity
This antibody reacts with high specificity to ß-HCG. This antibody does not detect FSH or MSH There is a slight reaction with LH
Tested applications
ELISA, IHC-Fr, IF, IHC-Pmore details
Cross reactivity
Reacts with
Human
Positive control
Placenta
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
PBS with 1% BSA and 10mM sodium azide
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
2092
Myeloma
unknown
Isotype
IgG1
Light chain type
unknown
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Developmental Biology >> Reproduction >> Hormones
Cancer >> Tumor biomarkers >> Hormones
Cancer >> Growth factors >> Hormones
Signal Transduction >> Growth Factors/Hormones >> Hormones
Applications
Show applications key
Our Abpromise guarantee covers the use of ab8466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
IHC-Fr
IF
IHC-P
Application notes
Cannot be used for RIA with radio-labeled antigen.
For tissue sections, dilute 1:5-1:25 with PBS
Target
Relevance
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Cellular localization
Secreted
Alternative names
- Anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG ALPHA antibody
- CG beta a antibody
see all
Database links
- Entrez Gene: 1082 Human
- Omim: 118860 Human
- SwissProt: P01215 Human
- SwissProt: P01233 Human
References for Anti-hCG antibody [2092] (ab8466)
ab8466 has not yet been referenced specifically in any publications.
Publishing research using ab8466? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"