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Anti-hCG antibody [2092] (ab8466)

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Overview

Product name

Anti-hCG antibody [2092]
See all hCG products (18) ...

Description

Mouse monoclonal [2092] to hCG

Specificity

This antibody reacts with high specificity to ß-HCG. This antibody does not detect FSH or MSH There is a slight reaction with LH

Tested applications

ELISA, IHC-Fr, IF, IHC-Pmore details

Cross reactivity

Reacts with

Human

Positive control

Placenta

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

PBS with 1% BSA and 10mM sodium azide

Concentration

Concentration information loading...

Purity

IgG fraction

Clonality

Monoclonal

Clone number

2092

Myeloma

unknown

Isotype

IgG1

Light chain type

unknown

Applications

Show applications key

Our Abpromise guarantee covers the use of ab8466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     
  • IHC-Fr

     
  • IF

     
  • IHC-P

     

Application notes

Cannot be used for RIA with radio-labeled antigen.
For tissue sections, dilute 1:5-1:25 with PBS

Target

Relevance

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Cellular localization

Secreted

Alternative names

  • Anterior pituitary glycoprotein hormones common subunit alpha antibody
  • CG ALPHA antibody
  • CG beta a antibody
  • CG beta antibody
  • CGA antibody
  • CGB antibody
  • CGB1 antibody
  • CGB2 antibody
  • CGB3 antibody
  • CGB5 antibody
  • CGB7 antibody
  • CGB8 antibody
  • Choriogonadotropin alpha chain antibody
  • Choriogonadotropin subunit beta antibody
  • Chorionic gonadotrophin alpha subunit antibody
  • Chorionic gonadotrophin chain beta antibody
  • Chorionic gonadotropin alpha polypeptide antibody
  • Chorionic gonadotropin beta 3 subunit antibody
  • Chorionic gonadotropin beta 5 subunit antibody
  • Chorionic gonadotropin beta 7 subunit antibody
  • Chorionic gonadotropin beta 8 subunit antibody
  • Chorionic gonadotropin beta chain antibody
  • Chorionic gonadotropin beta polypeptide 1 antibody
  • Chorionic gonadotropin beta polypeptide 2 antibody
  • Chorionic gonadotropin beta polypeptide 5 antibody
  • Chorionic gonadotropin beta polypeptide 7 antibody
  • Chorionic gonadotropin beta polypeptide antibody
  • Chorionic gonadotropin beta subunit antibody
  • Follicle stimulating hormone alpha chain antibody
  • Follitropin alpha chain antibody
  • FSH alpha antibody
  • FSHA antibody
  • Glycoprotein hormones alpha chain precursor antibody
  • Glycoprotein hormones alpha polypeptide antibody
  • GPHA 1 antibody
  • GPHa antibody
  • GPHA1 antibody
  • hCGB antibody
  • Human Chorionic Gonadotropin antibody
  • LHA antibody
  • LSH alpha antibody
  • Luteinizing hormone alpha chain antibody
  • Lutropin alpha chain antibody
  • MGC119822 antibody
  • Thyroid stimulating hormone alpha chain antibody
  • Thyrotropin alpha chain antibody
  • TSH alpha antibody
  • TSHA antibody
see all

References for Anti-hCG antibody [2092] (ab8466)

ab8466 has not yet been referenced specifically in any publications.

Publishing research using ab8466? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"