Anti-hCG beta 1 epitope antibody [INN-hCG-2] (ab11388)

Overview

  • Product nameAnti-hCG beta 1 epitope antibody [INN-hCG-2]
  • Description
    Mouse monoclonal [INN-hCG-2] to hCG beta 1 epitope
  • SpecificityClone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains. Affinity constant = 4.8x108 L.mol-1.
  • Tested applicationsSuitable for: IHC-P, ELISA, RIAmore details
    Unsuitable for: Flow Cyt
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human CG.

Properties

Applications

Our Abpromise guarantee covers the use of ab11388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
  • Application notesIs unsuitable for Flow Cyt.
  • Target

    • RelevanceHuman chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. The beta subunit of chorionic gonadotropin (CG) is encoded by 6 highly homologous genes which are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta subunit gene.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • CG beta antibody
      • CGB antibody
      • Choriogonadotropin subunit beta antibody
      • hCGB antibody

    References for Anti-hCG beta 1 epitope antibody [INN-hCG-2] (ab11388)

    This product has been referenced in:
    • Woldemariam GA & Butch AW Immunoextraction-tandem mass spectrometry method for measuring intact human chorionic gonadotropin, free ß-subunit, and ß-subunit core fragment in urine. Clin Chem 60:1089-97 (2014). Read more (PubMed: 24899693) »

    See 1 Publication for this product

    Product Wall

    Application Immunoprecipitation
    Sample Human Cell lysate - other (from urine)
    Total protein in input 50 µg
    Specification from urine
    Immuno-precipitation step Protein G
    Username

    Abcam user community

    Verified customer

    Submitted Oct 22 2011

    DISCOUNT CODE: *** Expiration date: February 15, 2012 I am very pleased to hear you would like to submit an Abreview for ab11388 in IP. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an A...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"