Overview

  • Product nameAnti-HCLS1 antibody [24]
    See all HCLS1 primary antibodies
  • Description
    Mouse monoclonal [24] to HCLS1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human HCLS1 expressed in E.coli.

  • Positive control
    • Jurkat whole cell lysate
  • General notesab106204 may be stored at 2o to 8o for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody. Affinity = 1.92×109

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.02% Proclin
    Constituents: Tris HCl, Sodium citrate, pH 7.0
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number24
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106204 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 54 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionSubstrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • Tissue specificityExpressed only in tissues and cells of hematopoietic origin.
  • Sequence similaritiesContains 4 cortactin repeats.
    Contains 1 SH3 domain.
  • Developmental stageExpressed in early stage of myeloid and erythroid differentiation.
  • Post-translational
    modifications
    Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.
  • Cellular localizationMembrane. Cytoplasm. Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cortactin like antibody
    • CTTNL antibody
    • HCLS 1 antibody
    • Hcls1 antibody
    • HCLS1_HUMAN antibody
    • Hematopoietic cell specific Lyn substrate 1 antibody
    • Hematopoietic cell-specific LYN substrate 1 antibody
    • Hematopoietic lineage cell-specific protein antibody
    • HS 1 antibody
    • HS1 antibody
    • LckBP1 antibody
    • OTTHUMP00000215180 antibody
    • OTTHUMP00000215182 antibody
    • p75 antibody
    see all

Anti-HCLS1 antibody [24] images

  • Anti-HCLS1 antibody [24] (ab106204) at 1/1000 dilution + Jurkat whole cell lysate

    Predicted band size : 54 kDa

References for Anti-HCLS1 antibody [24] (ab106204)

ab106204 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"