Overview

  • Product nameAnti-HCLS1 antibody
    See all HCLS1 primary antibodies
  • Description
    Rabbit polyclonal to HCLS1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 361-391 of Human HCLS1 (NP_005326.2).

  • Positive control
    • MDA-MB231 cell line lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab116521 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab116521 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 54 kDa.

Target

  • FunctionSubstrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • Tissue specificityExpressed only in tissues and cells of hematopoietic origin.
  • Sequence similaritiesContains 4 cortactin repeats.
    Contains 1 SH3 domain.
  • Developmental stageExpressed in early stage of myeloid and erythroid differentiation.
  • Post-translational
    modifications
    Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.
  • Cellular localizationMembrane. Cytoplasm. Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cortactin like antibody
    • CTTNL antibody
    • HCLS 1 antibody
    • Hcls1 antibody
    • HCLS1_HUMAN antibody
    • Hematopoietic cell specific Lyn substrate 1 antibody
    • Hematopoietic cell-specific LYN substrate 1 antibody
    • Hematopoietic lineage cell-specific protein antibody
    • HS 1 antibody
    • HS1 antibody
    • LckBP1 antibody
    • OTTHUMP00000215180 antibody
    • OTTHUMP00000215182 antibody
    • p75 antibody
    see all

Anti-HCLS1 antibody images

  • Anti-HCLS1 antibody (ab116521) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

    Predicted band size : 54 kDa

References for Anti-HCLS1 antibody (ab116521)

ab116521 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116521.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"