Anti-HDAC10 antibody - Aminoterminal end (ab71215)

Overview

  • Product nameAnti-HDAC10 antibody - Aminoterminal end
    See all HDAC10 primary antibodies
  • Description
    Rabbit polyclonal to HDAC10 - Aminoterminal end
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from a region of human HDAC10 within amino acids 1-100.

  • Positive control
    • A375 cell line lysate and 293 cell lysate transiently transfected with the HDAC10 gene.

Properties

Applications

Our Abpromise guarantee covers the use of ab71215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).

Target

  • FunctionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  • Tissue specificityUbiquitous. High expression in liver, spleen, pancreas and kidney.
  • Sequence similaritiesBelongs to the histone deacetylase family. HD type 2 subfamily.
  • Cellular localizationCytoplasm. Nucleus. Excluded from the nucleoli.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZP761B039 antibody
    • HD 10 antibody
    • HD10 antibody
    • HDA10_HUMAN antibody
    • HDAC 10 antibody
    • Hdac10 antibody
    • Histone deacetylase 10 antibody
    • MGC149722 antibody
    • OTTHUMP00000028555 antibody
    see all

Anti-HDAC10 antibody - Aminoterminal end images

  • Anti-HDAC10 antibody - Aminoterminal end (ab71215) at 1/100 dilution + A375 cell line lysates at 12.5 µg

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 150 kDa,90 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-HDAC10 antibody - Aminoterminal end (ab71215) at 1/100 dilution

    Lane 1 : 293 cell lysates non transfected
    Lane 2 : 293 cell lysates transiently transfected with the HDAC10 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

References for Anti-HDAC10 antibody - Aminoterminal end (ab71215)

ab71215 has not yet been referenced specifically in any publications.

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