Overview

  • Product name
    Anti-HDAC10 antibody [EPR3576]
    See all HDAC10 primary antibodies
  • Description
    Rabbit monoclonal [EPR3576] to HDAC10
  • Tested applications
    Suitable for: WB, IP, ICCmore details
    Unsuitable for: Flow Cyt or IHC-P
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human HDAC10

  • Positive control
    • HeLa, 293T, Jurkat, HepG2, A673 and NIH/3T3 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab108934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 75 kDa.
IP 1/10 - 1/100.
ICC 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt or IHC-P.
  • Target

    • Function
      Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • Tissue specificity
      Ubiquitous. High expression in liver, spleen, pancreas and kidney.
    • Sequence similarities
      Belongs to the histone deacetylase family. HD type 2 subfamily.
    • Cellular localization
      Cytoplasm. Nucleus. Excluded from the nucleoli.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZP761B039 antibody
      • HD 10 antibody
      • HD10 antibody
      • HDA10_HUMAN antibody
      • HDAC 10 antibody
      • Hdac10 antibody
      • Histone deacetylase 10 antibody
      • MGC149722 antibody
      • OTTHUMP00000028555 antibody
      see all

    Anti-HDAC10 antibody [EPR3576] images

    • All lanes : Anti-HDAC10 antibody [EPR3576] (ab108934) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : HepG2 cell lysate
      Lane 5 : A673 cell lysate
      Lane 6 : NIH/3T3 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 75 kDa

    References for Anti-HDAC10 antibody [EPR3576] (ab108934)

    This product has been referenced in:
    • Mondello P  et al. Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265 mutations. JCI Insight 2:e90196 (2017). WB ; Human . Read more (PubMed: 28352655) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab108934.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up