Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab41712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-HDAC10 antibody (ab18971)

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • DKFZP761B039
    • HD 10
    • HD10
    • HDA10_HUMAN
    • HDAC 10
    • Hdac10
    • Histone deacetylase 10
    • MGC149722
    • OTTHUMP00000028555
    see all
  • Function
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  • Tissue specificity
    Ubiquitous. High expression in liver, spleen, pancreas and kidney.
  • Sequence similarities
    Belongs to the histone deacetylase family. HD type 2 subfamily.
  • Cellular localization
    Cytoplasm. Nucleus. Excluded from the nucleoli.
  • Information by UniProt

References

ab41712 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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