• Product nameAnti-HDAC11 antibody
    See all HDAC11 primary antibodies
  • Description
    Rabbit polyclonal to HDAC11
  • Specificityab18973 recognises 39 kDa HDAC-11 of human and mouse origin. It also reacts with rat weakly.
  • Tested applicationsSuitable for: IHC-FoFr, WB, ICC/IF, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids surrounding 269 of Human HDAC 11

  • Positive control
    • Jurkat cell lysate, Mouse intestine tissue lysate.


Associated products


Our Abpromise guarantee covers the use of ab18973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesIHC-FoFr: Use at an assay dependent dilution (PMID 17893925).
    WB: Use at a concentration of 1 - 4 µg/ml. Predicted molecular weight: 39 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • Tissue specificityWeakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
    • Sequence similaritiesBelongs to the histone deacetylase family.
    • Cellular localizationNucleus. Predominantly nuclear.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ22237 antibody
      • HD 11 antibody
      • HD11 antibody
      • HDA11_HUMAN antibody
      • HDAC 11 antibody
      • HDAC11 antibody
      • Histone deacetylase 11 antibody
      see all

    Anti-HDAC11 antibody images

    • All lanes : Anti-HDAC11 antibody (ab18973) at 2.5 µg/ml

      Lane 1 : Jurkat cell lysate
      Lane 2 : Mouse intestine tissue lysate

      Predicted band size : 39 kDa

    References for Anti-HDAC11 antibody (ab18973)

    This product has been referenced in:
    • Liu J  et al. Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells. J Transl Med 14:7 (2016). Human . Read more (PubMed: 26747087) »
    • Tiwari S  et al. Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol 14:30 (2014). WB, IHC-Fr ; Mouse . Read more (PubMed: 25011550) »

    See all 8 Publications for this product

    Product Wall

    Application Flow Cytometry
    Fixation Paraformaldehyde
    Permeabilization Yes - BD permeabilization buffer
    Sample Mouse Cell (Mouse thymus tissue, thymocytes)
    Specification Mouse thymus tissue, thymocytes
    Gating Strategy CD45 positives
    Preparation Cell harvesting/tissue preparation method: Digestion with Collagenase D
    Sample buffer: PBS 2% FCS

    Mr. Sanjay Gawade

    Verified customer

    Submitted Jan 26 2015

    Thank you for your reply and for the nice feedback. I am happy the information was helpful to you.

    I have issued a credit note for the value of the antibody ab18973.

    Your credit note ID is XXXXX.

    The credit note may be use...

    Read More

    Thank you for your reply.

    Any of the alternatives anti HDAC11 validated in WB with mouse samples should work as stated on the datasheet. There are 4 http://www.abcam.com/index.html?pageconfig=searchresults&search=HDAC11&pt=1&sk=re...

    Read More

    Thank you very much for taking the time to complete our questionnaire and sending the images.

    I am sorry to hear you have been experiencing problems with one of our antibodies. The quality of our products is important to us and I would like t...

    Read More

    Thank you for your enquiry. Unfortunately I do not have access to the Bradbury publication. However, I can tell you that ab18973; Rabbit polyclonal to HDAC11 was not in our catalogue until 02 Nov 05. Therefore given the date of publication I consid...

    Read More