Overview

  • Product nameAnti-HDAC3 antibody - ChIP Grade
    See all HDAC3 primary antibodies
  • Description
    Rabbit polyclonal to HDAC3 - ChIP Grade
  • Tested applicationsSuitable for: WB, IP, ChIPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    GST fusion of the full-length human HDAC3.

Applications

Our Abpromise guarantee covers the use of ab96005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 49 kDa.
IP Use at an assay dependent dilution.
ChIP Use at an assay dependent dilution.

Target

  • FunctionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the histone deacetylase family. HD type 1 subfamily.
  • Post-translational
    modifications
    Sumoylated in vitro.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HD3 antibody
    • HDAC 3 antibody
    • HDAC3 antibody
    • HDAC3_HUMAN antibody
    • Histone deacetylase 3 antibody
    • RPD3 2 antibody
    • RPD3 antibody
    • RPD3-2 antibody
    • SMAP45 antibody
    see all

Anti-HDAC3 antibody - ChIP Grade images

  • Anti-HDAC3 antibody - ChIP Grade (ab96005) at 1/2000 dilution + HeLa

    Predicted band size : 49 kDa
    Observed band size : 49 kDa

References for Anti-HDAC3 antibody - ChIP Grade (ab96005)

ab96005 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96005.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"