Overview

  • Product nameAnti-HEL antibody [5F12]
  • Description
    Mouse monoclonal [5F12] to HEL
  • SpecificitySpecific to Hexanoyl-Lys adducts.
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Immunogen

    Chemical/ Small Molecule conjugated to KLH: Nepsilon hexanoyl-Keyhole limpet hemocyanin (HEL-KLH)

Properties

Applications

Our Abpromise guarantee covers the use of ab93056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    IHC-P: Use at a concentration of 2 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceOxidative damage of lipids caused by reactive oxygen species (ROS) play an important role in some diseases, lesion of cell functions and aging. Aldehydes such as malondi-aldehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) have been reported as one of the advanced lipid peroxidation products. But recently in the earlier stage of lipid peroxidation, 13-hydroperoxyoctadecanoic acid (13-HPODE) is found to be covalently bound to proteins1). Hexanoyl-Lysine adduct (HEL) is a novel lipid hydroperoxide-modified lysine residues. HEL is formed by oxidative modification by oxidized omega 6 fatty acids such as linoleic acid or arachidonic acid.
    • Alternative names
      • HEL antibody
      • Hexanoyl Lys antibody

    References for Anti-HEL antibody [5F12] (ab93056)

    ab93056 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"