Overview

  • Product nameAnti-Helicobacter pylori antibody
    See all Helicobacter pylori primary antibodies
  • Description
    Rabbit polyclonal to Helicobacter pylori
  • SpecificityWhole cell lysate. Has not been absorbed and may react with related microorganisms.
  • Tested applicationsSuitable for: ELISA, ICC/IF, Conjugation, IHC-Pmore details
  • Species reactivity
    Reacts with Helicobacter pylori. Not yet tested in other species.
  • Immunogen

    ATCC strain 43504

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notes>95% pure
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
ICC/IF 1/1000.
Conjugation Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • RelevanceThe spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
  • Alternative names
    • H. pylori antibody

References for Anti-Helicobacter pylori antibody (ab20459)

This product has been referenced in:
  • Hoppe S  et al. Rapid identification of novel immunodominant proteins and characterization of a specific linear epitope of Campylobacter jejuni. PLoS One 8:e65837 (2013). Read more (PubMed: 23734261) »
  • Rossez Y  et al. Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori. Glycobiology 22:1193-206 (2012). Read more (PubMed: 22522599) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"