Overview

  • Product name
    Anti-Helicobacter pylori antibody
    See all Helicobacter pylori primary antibodies
  • Description
    Rabbit polyclonal to Helicobacter pylori
  • Tested applications
    Suitable for: IHC-FoFr, IHC-Pmore details
  • Immunogen

    Purified from heat-treated cells of H. pylori strain, CH20429.

  • General notes


    This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    20 mM tris-borate, 150 mM sodium chloride,0.1% sodium azide
  • Concentration information loading...
  • Primary antibody notes
    This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab7788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration.
IHC-P 1/5 - 1/10. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. Prolonged fixation in buffered formanlin may destroy the epitope.

Target

  • Relevance
    The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
  • Alternative names
    • H. pylori antibody

Images

  • ab7788 stainning formalin-fixed/ paraffin-embbeded human stomach tissue sections infected with Helicobacter pylori.

References

This product has been referenced in:
  • Itthitaetrakool U  et al. Chronic Opisthorchis viverrini Infection Changes the Liver Microbiome and Promotes Helicobacter Growth. PLoS One 11:e0165798 (2016). IHC-P . Read more (PubMed: 27806126) »
  • Li ZW  et al. Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia. World J Gastroenterol 16:1788-94 (2010). IHC-P . Read more (PubMed: 20380014) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for contacting us.

Unfortunately we do not have this exact antibody conjugated to HRP in our catalogue nor can we get it from our lab. However, we recommend using ab6721 (http://www.abcam.com/ab6721) as a secondary antibody to thi...

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Thank you for contacting us.

We do not have any experimental data regarding the cross-reactivity of E3014 with rodentium.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice ...

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Thank you for your enquiry and for your patience. It has taken some time to obtain this information for you.

I am sorry to confirm that our Helicobacter pylori antibodies have not been tested specifically for detection of the SS1 strain. Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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