Recombinant
RabMAb

Anti-Helicobacter pylori antibody [EPR10353] (ab172611)

Overview

  • Product name
    Anti-Helicobacter pylori antibody [EPR10353]
    See all Helicobacter pylori primary antibodies
  • Description
    Rabbit monoclonal [EPR10353] to Helicobacter pylori
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Immunogen

    Tissue, cells or virus corresponding to Helicobacter pylori.

  • Positive control
    • Human gastritis tissue.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.01% Sodium azide
    Constituents: 49% PBS, 0.05% BSA, 50% Glycerol
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR10353
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab172611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
  • Alternative names
    • H. pylori antibody

Images

  • Immunohistochemical analysis of paraffin-embedded Human gastritis tissue labeling Helicobacter pylori with ab172611 at 1/250 dilution (left panel) and Human stomach tissue (negative control) (right panel).

References

ab172611 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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