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Product Name
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Helicobacter pylori antibody (HRP)
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See all Helicobacter pylori antibodies (13)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Helicobacter pylori (HRP)
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Immunogen
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Tissue / cell preparation (ATCC strain 43504).
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Species Reactivity
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Has not been absorbed and may react with related microorganisms.
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Tested applications
(see key)
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ELISA, IHC-FoFr
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA: 1/20 - 1/1000. IHC-F: 1/20 - 1/200.
Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Microbiology >> Organism >> Bacteria >> Gram negative Bacteria >> Helicobacter
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Relevance
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The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Conjugation notes
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Estimated molar HRP:IgG substitution is 2-3.
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Storage buffer
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Preservative: 0.002% Thimerosal (merthiolate). Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase. Constituents: PBS, 10mg/ml BSA Material safety datasheet (MSDS) for this product: Thimerosal MSDS
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Purification notes
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Source: whole cell lysate. Protein A chromatography purified IgG fraction covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is absent.
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Form
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Liquid
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Conjugation
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Horse Radish Peroxidase
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Helicobacter pylori antibody (HRP) is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Helicobacter pylori
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Helicobacter pylori antibody (HRP) - more information
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