DyLight® 488 Anti-Hemagglutinin antibody (ab117493)
Key features and details
- DyLight® 488 Rabbit polyclonal to Hemagglutinin
- Suitable for: ICC/IF
- Reacts with: Influenza A
- Conjugation: DyLight® 488. Ex: 493nm, Em: 518nm
- Isotype: IgG
Overview
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Product name
DyLight® 488 Anti-Hemagglutinin antibody
See all Hemagglutinin primary antibodies -
Description
DyLight® 488 Rabbit polyclonal to Hemagglutinin -
Host species
Rabbit -
Conjugation
DyLight® 488. Ex: 493nm, Em: 518nm -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 1.6% Sodium phosphate, 0.88% Sodium chloride, 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab117493 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
1/500 - 1/5000.
|
Notes |
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ICC/IF
1/500 - 1/5000. |
Target
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Relevance
Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains. -
Cellular localization
Cell membrane; apical cell membrane; single-pass type I membrane protein. -
Database links
- Entrez Gene: 3654620 Influenza A
- SwissProt: C3W5S1 Influenza A
- SwissProt: Q0HD60 Influenza A
- SwissProt: Q9Q0U6 Influenza A
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Alternative names
- HA antibody
- HA1 antibody
- HA2 antibody
- Hemagglutinin antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab117493 has not yet been referenced specifically in any publications.