Overview

  • Product nameAnti-Hemoglobin A1c antibody
    See all Hemoglobin A1c primary antibodies
  • Description
    Duck polyclonal to Hemoglobin A1c
  • SpecificityThis antibody is specific to Hemoglobin A1c.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Hemoglobin A1c.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.14M Sodium chloride, 10mM PBS, pH 7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurity was determined by SDS PAGE (blue stain), showing that the IgY(delta Fc) constitute was 90% of total protein, and the IgY and IgY (delta Fc) constitute was 95% of total protein.
  • ClonalityPolyclonal
  • IsotypeIgY
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab31151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: 1/5000.
    Immunochromatography: Use at an assay dependent dilution.
    Immunoturbidimetry: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in oxygen transport from the lung to the various peripheral tissues.
      LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure.
      Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
    • Tissue specificityRed blood cells.
    • Involvement in diseaseHeinz body anemias
      Beta-thalassemia
      Sickle cell anemia
      Beta-thalassemia, dominant, inclusion body type
    • Sequence similaritiesBelongs to the globin family.
    • Post-translational
      modifications
      Glucose reacts non-enzymatically with the N-terminus of the beta chain to form a stable ketoamine linkage. This takes place slowly and continuously throughout the 120-day life span of the red blood cell. The rate of glycation is increased in patients with diabetes mellitus.
      S-nitrosylated; a nitric oxide group is first bound to Fe(2+) and then transferred to Cys-94 to allow capture of O(2).
      Acetylated on Lys-60, Lys-83 and Lys-145 upon aspirin exposure. PubMed:16916647 reports the identification of HBB acetylated on Lys-145 in the cytosolic fraction of HeLa cells. This may have resulted from contamination of the sample.
    • Information by UniProt
    • Database links
    • Alternative names
      • Beta-globin antibody
      • HBB antibody
      • HBB_HUMAN antibody
      • Hemoglobin beta chain antibody
      • Spinorphin antibody
      see all

    References for Anti-Hemoglobin A1c antibody (ab31151)

    ab31151 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab31151.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"