Overview

  • Product name
    Anti-Hepatitis B Virus Core Antigen antibody
    See all Hepatitis B Virus Core Antigen primary antibodies
  • Description
    Rabbit polyclonal to Hepatitis B Virus Core Antigen
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Hepatitis B virus
  • Immunogen

    Full length native protein (purified) corresponding to Hepatitis B Virus Core Antigen.

  • Positive control
    • Human liver tissue infected with Hepatitis B virus.

Properties

Applications

Our Abpromise guarantee covers the use of ab115992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/400.
IHC-Fr 1/200 - 1/400.

Target

  • Relevance
    Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
  • Cellular localization
    Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
  • Database links
    • Alternative names
      • C antibody
      • Capsid protein antibody
      • Core and e antigen antibody
      • core antibody
      • Core antigen antibody
      • Core protein antibody
      • HBc antibody
      • HBcAg antibody
      • HBVgp4 antibody
      • Hepatitis B core antigen antibody
      • Hepatitis B Virus core antigen antibody
      • p21.5 antibody
      • precore/core protein antibody
      see all

    References

    This product has been referenced in:
    • Wang Y  et al. Enhanced immunity and antiviral effects of an HBV DNA vaccine delivered by a DC-targeting protein. J Viral Hepat 23:798-804 (2016). Read more (PubMed: 27126208) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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