Anti-Hepatitis B Virus Core Antigen antibody (ab17228)

Overview

  • Product nameAnti-Hepatitis B Virus Core Antigen antibody
    See all Hepatitis B Virus Core Antigen primary antibodies
  • Description
    Rabbit polyclonal to Hepatitis B Virus Core Antigen
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with Hepatitis type B virus. Not yet tested in other species.
  • Immunogen

    HBcAg purified from the lysates of E.coli infected with the viral core DNA.

  • Positive control
    • Liver infected with the Hepatitis type B virus.
  • General notes


    This antibody detectes the antigen in the nuclei of the liver cells of the Hepatitis type B virus infected patients. However, occasional staining may also be seen in the perinuclear cytoplasm of the infected cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA
  • PurityWhole antiserum
  • Primary antibody notesThis antibody detectes the antigen in the nuclei of the liver cells of the Hepatitis type B virus infected patients. However, occasional staining may also be seen in the perinuclear cytoplasm of the infected cells.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/150.

 An incubation period of 30 minutes at room temperature is recommended.

Target

  • RelevanceHepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
  • Cellular localizationCapsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
  • Alternative names
    • C antibody
    • Capsid protein antibody
    • Core and e antigen antibody
    • Core antigen antibody
    • Core protein antibody
    • HBc antibody
    • HBcAg antibody
    • HBVgp4 antibody
    • Hepatitis B Virus core antigen antibody
    • p21.5 antibody
    • precore/core protein antibody
    see all

References for Anti-Hepatitis B Virus Core Antigen antibody (ab17228)

ab17228 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"