Anti-Hepatitis B Virus Core Antigen antibody [ABM021] (ab113620)

Overview

  • Product nameAnti-Hepatitis B Virus Core Antigen antibody [ABM021]
    See all Hepatitis B Virus Core Antigen primary antibodies
  • Description
    Mouse monoclonal [ABM021] to Hepatitis B Virus Core Antigen
  • SpecificityNo cross reaction was found with HBeAg , HBsAg, HCV and AFP.
  • Tested applicationsSuitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Hepatitis B virus
  • Immunogen

    Recombinant Hepatitis B Virus Core Antigen.

  • Positive control
    • Hepatitis B Virus Core Antigen positive samples.
  • General notesAFFINITY CONSTANT: 2x109 L/Mol.

Properties

Applications

Our Abpromise guarantee covers the use of ab113620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.

Target

  • RelevanceHepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
  • Cellular localizationCapsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
  • Database links
    • Alternative names
      • C antibody
      • Capsid protein antibody
      • Core and e antigen antibody
      • Core antigen antibody
      • Core protein antibody
      • HBc antibody
      • HBcAg antibody
      • HBVgp4 antibody
      • Hepatitis B Virus core antigen antibody
      • p21.5 antibody
      • precore/core protein antibody
      see all

    References for Anti-Hepatitis B Virus Core Antigen antibody [ABM021] (ab113620)

    ab113620 has not yet been referenced specifically in any publications.

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