Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (Biotin) (ab68520)

Overview

  • Product nameAnti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (Biotin)
    See all Hepatitis B Virus Surface Antigen (Ad/Ay) primary antibodies
  • Description
    Rabbit polyclonal to Hepatitis B Virus Surface Antigen (Ad/Ay) (Biotin)
  • ConjugationBiotin
  • SpecificityReacts with Hepatitis B Virus Surface Antigen in viral and infected tissue samples.
  • Tested applicationsSuitable for: WB, ELISA, ICC/IF, IHC-Frmore details
  • Species reactivity
    Reacts with: Hepatitis B virus
  • Immunogen

    Hepatitis B Virus Surface Antigen subtypes ad & ay.

Properties

Applications

Our Abpromise guarantee covers the use of ab68520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.

Target

  • RelevanceHepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
  • Cellular localizationVirion membrane
  • Database links
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  • Alternative names
    • HBsAg antibody
    • HBV major surface antigen antibody
    • HBV surface antigen antibody
    • Hepatitis B Virus major surface antigen antibody
    • Major surface antigen antibody
    • S antibody
    see all

References for Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (Biotin) (ab68520)

ab68520 has not yet been referenced specifically in any publications.

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