Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted (ab859)


  • Product nameAnti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted
    See all Hepatitis B Virus Surface Antigen primary antibodies
  • Description
    Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
  • SpecificityThis antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Immunogen

    BALB/c mice were immunized with purified HBsAG subtype AYW3.



Our Abpromise guarantee covers the use of ab859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesThis antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
    No further titration is required.
    We suggest an incubation period of 60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
  • Target

    • RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
    • Cellular localizationVirion membrane
    • Alternative names
      • Large envelope protein antibody
      • Large surface protein antibody
      • LHB antibody
      • Major surface antigen antibody

    References for Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted (ab859)

    ab859 has not yet been referenced specifically in any publications.

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    Thank you for your email.
    We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
    If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet ...

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    Regarding ab859 (Hepatitis B Virus Surface Antigen antibody [3E7], prediluted), the concentration of the present lot is 2 ug/ml. Please don't hesitate to contact us again if you have further questions.

    The final concentration of this prediluted antibody is 20ug/ml.