Overview

  • Product nameAnti-Hepatitis B Virus Surface Antigen antibody
    See all Hepatitis B Virus Surface Antigen primary antibodies
  • Description
    Rabbit polyclonal to Hepatitis B Virus Surface Antigen
  • SpecificityAb19979 reacts only with Hepatitis B surface antigen. Non-reactive with normal human serum.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Hepatitis B
  • Immunogen

    Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.

Properties

Applications

Our Abpromise guarantee covers the use of ab19979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: Use at an assay dependent dilution.

    May be used in place of whole antiserum in almost any appropriate antibody based technique. Also suitable for conjugation purposes.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
    • Cellular localizationVirion membrane
    • Alternative names
      • Large envelope protein antibody
      • Large surface protein antibody
      • LHB antibody
      • Major surface antigen antibody

    References for Anti-Hepatitis B Virus Surface Antigen antibody (ab19979)

    This product has been referenced in:
    • Schliehe C  et al. Stable antigen is most effective for eliciting CD8+ T-cell responses after DNA vaccination and infection with recombinant vaccinia virus in vivo. J Virol 86:9782-93 (2012). Read more (PubMed: 22761378) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"